Difference between revisions of "Interesting Things"
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− | ==== | + | ==== psychological and neurological influence on R&D management style? ==== |
− | [[ | + | |
− | more | + | over the last 10+ years there's been a growing body of evidence related to political, economic, and religious conservatism and brain structures or cognitive behavior related to sensitivity to perceived negative, uncertain, or ambiguous information. |
− | ==== | + | |
− | [http:// | + | for example, there's the 2014 study [http://www.cell.com/current-biology/abstract/S0960-9822(14)01213-5 Nonpolitical Images Evoke Neural Predictors of Political Ideology] published in Cell-Current Biology. To quote the researchers, "This is the first fMRI study revealing multivariate patterns of brain activity that differ between liberals and conservatives during emotional processing of sensory stimuli. A single disgusting image was sufficient to predict each subject's political orientation" with 94% accuracy, Montague told Cell Press. I haven't seen such clean predictive results in any other functional imaging experiments in our lab or others." |
+ | |||
+ | in other words, apparent 'conscious' and 'deliberative' decisions about political ideology are connected strongly to very primitive parts of the brain involved in aversion or fear responses. | ||
+ | |||
+ | another study: [http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=9292100&fulltextType=RA&fileId=S0140525X13001192 a 2014 study] shows that self-reported conservatives respond with fear much more rapidly to what they perceive as aversive or threatening stimuli. | ||
+ | |||
+ | linking to neurology, [http://www.cell.com/current-biology/abstract/S0960-9822(11)00289-2 a report] in Current Biology shows evidence that young adults that self-describe as politically liberal or conservative have different brain structures. the self-described conservatives have a larger amygdala (related to fear responses) and "respond to threatening situations with more aggression than do liberals and are more sensitive to threatening facial expressions." the liberals have larger anterior cingulate cortexes, that "monitor(s) uncertainty and conflicts." to quote: "Thus, it is conceivable that individuals with a larger ACC have a higher capacity to tolerate uncertainty and conflicts, allowing them to accept more liberal views." | ||
+ | |||
+ | linking back to psychology research is a [http://faculty.virginia.edu/haidtlab/jost.glaser.political-conservatism-as-motivated-social-cog.pdf published synthesis] of existing psychological studies on ideology, shows a pattern of evidence that conservatives are characterized by traits such as a need for certainty and an intolerance of ambiguity. | ||
+ | |||
+ | and there's related research on the [http://link.springer.com/article/10.1007%2FBF02686907 lack of tolerance of ambiguity] and [http://onlinelibrary.wiley.com/doi/10.1002/9781444344073.ch1/summary the need for certainty] being stronger amongst self-reported conservatives. | ||
+ | |||
+ | as mentioned in another blog post, in my product development management consulting work, i observe managers have widely differing ability to accept the inherent high level uncertainty and variability of research and development product creation. some really want R&D to be "predictable manufacturing" and have ''psychological'' discomfort with a domain of uncertainty that requires feedback loops, learning, and revision of prior information (estimates, requirements, ...). perhaps there is a correlation to this research. | ||
+ | |||
+ | ==== a fast way to stem-cell-based regeneration ==== | ||
+ | [http://www.cell.com/cell-stem-cell/pdf/S1934-5909(14)00151-9.pdf Research] published in ''Cell Stem Cell'' that a minimum 48-hour fast helps "regenerate" the immune system, and a minimum 72-hour fast helped recovery during chemotherapy. Rinse & repeat every 6 months. | ||
+ | |||
+ | ==== how to survive a plane crash & cognitive bias ==== | ||
+ | most people will be drawn to read this article on [http://www.livescience.com/38015-how-to-survive-a-plane-crash-ntsb.html surviving a plane crash] as an example of ''cognitive bias'', even though they are more likely to die in a car crash. | ||
+ | |||
+ | this cognitive bias is an example of a larger set: | ||
+ | * Confirmation Bias | ||
+ | * Ingroup Bias | ||
+ | * Gambler's Fallacy | ||
+ | * Positive expectation bias | ||
+ | * Post-Purchase Rationalization | ||
+ | * Neglecting Probability | ||
+ | * Observational Selection Bias | ||
+ | * Status-Quo Bias | ||
+ | * Negativity Bias | ||
+ | * Bandwagon Effect | ||
+ | * Projection Bias | ||
+ | * The Current Moment Bias | ||
+ | * Anchoring Effect | ||
+ | |||
+ | and wikipedia has a [https://en.wikipedia.org/wiki/List_of_cognitive_biases wonderful list] of over *SIXTY* kinds of cognitive bias. | ||
+ | |||
+ | related are the insights of charlie munger, the partner of warren buffet ("the greatest investor") in his 1995 harvard talk [http://boingboing.net/2013/03/02/twenty-four-standard-causes-of.html Twenty Four Standard Causes of Human Misjudgement] | ||
+ | |||
+ | ==== could be big (meaning, little) ==== | ||
+ | University of Illinois researchers have created a breakthrough battery technology orders of magnitude smaller and more powerful. [http://www.bbc.co.uk/news/technology-22191650 here's the story]. | ||
+ | |||
+ | ==== 30 gram micro-drone with camera; bionic dragonfly ==== | ||
+ | not hard to see the trajectory of this technology. even the first generation micro-drone with 30 minutes of flying time with real-time transmission of video is a mere 30 grams. imagine in 10 years. these have now been issued to british soldiers in combat zones. [https://www.youtube.com/watch?v=FBxmck16FhA video here] | ||
+ | |||
+ | and [https://www.youtube.com/watch?feature=player_embedded&v=nj1yhz5io20 here is a bionic dragonfly], which will be commercialized soon. amazing | ||
+ | |||
+ | ==== hard data on dominant cause of unhappiness: wandering mind ==== | ||
+ | for his phd research at harvard in 2012, matt killingsworth used mobile app and big data tools to identify a dominant ''cause'' (not just correlate) of unhappiness: a wandering mind not focussed in the sensations of the present moment. [http://www.ted.com/talks/matt_killingsworth_want_to_be_happier_stay_in_the_moment.html watch the TED talk here.] he did not discuss therapies or mental tools, but there are several. for example, [https://en.wikipedia.org/wiki/Charlotte_Selver charlotte selver] was a music educator who founded and promoted ''sensory awareness'' training, that led to variants such as ''body awareness therapy'' and ''somatic therapy'', and [https://en.wikipedia.org/wiki/Mindfulness-based_stress_reduction mindfulness-based stress reduction] (coming from the university of massachusetts medical school). | ||
+ | |||
+ | going farther back, "mindfulness of physical sensations" (such as breathing, touch pressure, etc.) is a buddhist practice in the theravada school (the oldest branch of the doctrine) and practiced in 'mindfulness' retreats. | ||
+ | |||
+ | ==== scientific evidence of absence of free will ==== | ||
+ | if you choose to [http://io9.com/5975778/scientific-evidence-that-you-probably-dont-have-free-will click this link] and read the evidence, who made that choice? | ||
+ | |||
+ | ==== cheating with 'undetectable' chess computer aid ==== | ||
+ | in bulgaria in dec 2012 a chess tournament was held in which a player displayed a leap of improved playing that was so suspicious that organizers suspect aid from a computer. but it was not possible to detect anything on the player in question. people speculate about an under-the-skin implant that transmits information, but there is no proof. what is interesting about this story is that it is the first harbinger of things to come, more broadly in the area of bionics and neuro-prosthetics. one analyst presents an interesting study on how to evaluate if the cheater was using a computer, with statistics. [https://rjlipton.wordpress.com/2013/01/13/the-crown-game-affair/ read here.] | ||
+ | |||
+ | ==== causation vs. correlation ==== | ||
+ | '''convergent cross mapping'''. a research result that might not sound a milestone, but probably is: finally, a solid mathematical model to answer the question, "Is there a causal relationship between 2 factors?". And that answer can now be provided (for biological and eco systems), even without knowing the details of the underlying mechanisms. summarized in the paper [http://ucsdnews.ucsd.edu/pressrelease/scripps_led_team_takes_on_centuries_old_cause_and_effect_problem Detecting Causality in Complex Ecosystems]. | ||
+ | |||
+ | ==== is it real -- or Memorex? ==== | ||
+ | perhaps if you read the original ''Nature Neuroscience'' title, ''Mnemonic representations of transient stimuli and temporal sequences in the rodent hippocampus in vitro'', the fact and implications may not be clear. how about this summary? [http://gizmodo.com/5942291/scientists-invent-method-to-create-memories-in-brains Scientists Invent Method to Create Memories in Brains]. wow. | ||
+ | |||
+ | ==== MIT people see more clearly ==== | ||
+ | could be big: to [http://www.mit.edu/newsoffice/2012/glare-dust-and-fog-free-glass-0426.html quote], "''MIT researchers find a way to make glass that’s anti-fogging, self-cleaning and free of glare''." | ||
+ | |||
+ | ==== the advanced british spy service ==== | ||
+ | hard to resist a [http://www.telegraph.co.uk/news/uknews/crime/ headline] that reads "''Sadomasochism interest no barrier to dead spy joining MI6''". how do they do the interviews? | ||
+ | |||
+ | ==== bionic eye patient tests planned for 2013 ==== | ||
+ | link [http://www.techworld.com.au/article/422918/bionic_eye_patient_tests_planned_2013/ here]. what more to say? we live in amazing times. | ||
+ | |||
+ | ==== discovered? the mechanism of memory encoding ==== | ||
+ | |||
+ | this [http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002421 research] could be a profound milestone in science; it hints at the real core, subtle mechanism of memory encoding. it involves interaction of calcium-calmodulin dependent kinase complex II and tubulin protein compounds, which occupy the interiors of brain neurons. | ||
+ | |||
+ | ==== cancer "cure" ignored due to no profit? ==== | ||
+ | interesting story out of the University of Alberta, regarding [https://en.wikipedia.org/wiki/Dichloroacetic_acid dichloroacetic acid]. Here'a related [http://www.foxnews.com/health/2011/05/18/big-pharma-ignoring-potential-cancer-cure/ news story] on the profit motive and lack of follow-up research. | ||
+ | |||
+ | ==== influenza A antibody ==== | ||
+ | one vaccine for all forms of influenza A is a long-sought goal. researchers [http://www.cidrap.umn.edu/cidrap/content/influenza/general/news/jul2911antibody.html now report] the discovery of FI6 antibody that binds to and neutralizes all subtypes. to find a potential antibody, they used a "wide search" strategy single-cell culture method to screen 100,000 plasma cells from eight human donors. Four of those 100,000 cells "from one donor yielded an antibody that reacted with H1, H5, and H7 viruses." | ||
+ | |||
+ | ==== who can resist reading a news items titled... ==== | ||
+ | [http://www.telegraph.co.uk/news/uknews/crime/8670520/Harry-Potter-dwarf-spared-jail-over-jugglers-hat-sex-act.html Harry Potter dwarf spared jail over juggler's hat sex act] | ||
+ | |||
+ | ==== brain on a plate ==== | ||
+ | researchers at the university of pittsburgh have grown an active "living" partial rat brain in a [http://scienceblogs.com/deanscorner/2011/05/growing_a_brain_in_a_dish.php dish]. | ||
+ | |||
+ | ==== big ==== | ||
+ | prediction: within 20 years, [http://www.youtube.com/watch?v=hZCiqkWCLqw something like this] is going to be huge. this is an entire mobile phone based on [http://www.youtube.com/watch?v=Rl-qygUEE2c this important trend]. this will revolutionize the form factor of devices. probably in tube or scroll-style -- check out seconds 42-49 in the first video. | ||
+ | |||
+ | longer term? probably the ability to replace the biological lens of the eyeball with artificial lens that display (via wireless signals) images. | ||
+ | |||
+ | ==== nobiletin ==== | ||
+ | nobiletin, found in the skin of tangerines, is a citrus flavonoid [http://diabetes.diabetesjournals.org/content/early/2011/04/04/db10-0589.abstract recently shown] in mice studies to have strongly attenuated atherosclerosis and VLDL overproduction, and reduced obesity. | ||
+ | |||
+ | ==== 800 lumens, 20 years, 8 watts ==== | ||
+ | there is some [http://www.telegraph.co.uk/health/8462626/Energy-saving-light-bulbs-contain-cancer-causing-chemicals.html very tentative research] that CFL lights may have carcinogenic issues, but fortunately, LED home lighting is [http://news.cnet.com/8301-11128_3-20016005-54.html now emerging]. | ||
+ | |||
+ | ==== no, no, no ==== | ||
+ | the youtube commenter probably said it best, ''"if he fell he would probably land on his gigantic balls and survive.''" this is just a little out of my comfort [http://www.youtube.com/watch?v=G-dPjDYVKUY zone]. | ||
+ | |||
+ | ==== the magician ==== | ||
+ | the wonderful, colorful physicist [http://en.wikipedia.org/wiki/Richard_feynman richard feynman] gave a series of lectures on physics, that have long been famous for their approach. they are now online, and well worth [http://research.microsoft.com/apps/tools/tuva/#data=2%7C6b89dded-3eb8-4fa4-bbcd-7c69fe78ed0c%7C%7C watching]. | ||
+ | |||
+ | at los alamos, during the a-bomb project, the science leader oppenheimer said of feynman (and consider the competition there!), ''"He is by all odds the most brilliant young physicist here, and everyone knows this"''. | ||
+ | |||
+ | ==== online documentaries ==== | ||
+ | while surfing for the Watson AI video, stumbled across a nice streaming documentary site, that organizes videos mostly from youtube: [http://documentarystorm.com/ DocumentaryStorm] | ||
+ | |||
+ | ==== an AI milestone ==== | ||
+ | the "AI" system [http://en.wikipedia.org/wiki/Watson_(artificial_intelligence_software) Watson] created by researchers at IBM and several universities, that won the [http://documentarystorm.com/science-tech/smartest-machine-on-earth ''Jeopardy!'' TV game show], is the first example seen (observing since the 1970s) of a computer system that made me go, "wow, finally getting somewhere interesting with AI research." will be fascinating to see how the "deep QA" ideas applied in Watson are put to practical use; for example, IBM is now implementing [http://www.google.com/hostednews/ap/article/ALeqM5gUcOBLoEFR1Zl012vgqM1puTRq9Q?docId=538a2d727d2448bda056fc5ab2ffd4e9 "medical Watson"] for commercialization. | ||
+ | |||
+ | ==== never too old ==== | ||
+ | good for [http://www.guardian.co.uk/lifeandstyle/2011/apr/02/i-am-a-90-year-old-bodybuilder him]! and good for [http://www.washingtonpost.com/lifestyle/magazine/ernestine-shepherd-in-shape-at-age-74/2011/05/24/AGWRuqCH_gallery.html her] | ||
+ | |||
+ | ==== coach potato marathon mouse ==== | ||
+ | slim, healthy, super fit endurance athlete body -- not by exercising, but by [http://en.wikipedia.org/wiki/AICA_ribonucleotide AICAR]? | ||
+ | |||
+ | salk institute researchers discovered that a key dynamic of slow-twitch muscle endurance exercise (e.g., jogging) is that it triggers the development of more mitochondria that burn fat. and AICAR stimulates this same biochemical process, stimulating the creation of more slow-twitch muscles and fat-burning mitochondria. they did an experiment with mice that were sedentary for months, but fed AICAR daily. the first noteworthy thing was that the coach-potato mice remained slim and healthy looking. and then, without any prior exercise or training, the coach potato mice were put in a high-endurance marathon tread mill run -- and were immediately a champion "marathon mice" that could exercise for a long. | ||
+ | |||
+ | as the researchers point out, this drug could be useful for old people or others who are temporarily bed ridden and quickly losing muscle tone. | ||
+ | |||
+ | ==== where did i leave my walking shoes? ==== | ||
+ | a recent study published in [http://www.pnas.org/content/108/7/3017 PNAS] showed that 40 minutes 3 times per week (for 1 year) of brisk walking (an aerobic activity) for a group of (prior-sedentary) seniors increased hippocampal and medial temporal lobe volumes by 2%, and was concomitantly associated with improved cognitive/memory function. OTOH, a matched group that only did stretching exercises degraded. | ||
+ | |||
+ | ==== e-eyes ==== | ||
+ | interesting for bifocal or progressive glass lens wearers: the introduction of dynamic electronic focusing lens, [http://www.pixeloptics.com/index.html emPower]. the technology is described as "the single most significant advancement in prescription eyewear in the last 50 years" -- that might be true. | ||
+ | |||
+ | ==== fists of fury? ==== | ||
+ | a [http://www.physorg.com/news/2010-10-clenching-muscles-willpower.html study] published in ''journal of consumer research'' showed that clenching muscles (such as a fist) was associated with increased self-control, such as resisting your third helping of chocolate mousse. To quote: ''Participants who were instructed to tighten their muscles, regardless of which muscles they tightened—hand, finger, calf, or biceps—while trying to exert self-control demonstrated greater ability to withstand the pain, consume the unpleasant medicine, attend to the immediately disturbing but essential information, or overcome tempting foods.'' | ||
+ | |||
+ | ==== Thacker -- Turing award ==== | ||
+ | another PARC alumni (in addition to Alan Kay and Butler Lampson) has won the Turing award. [http://en.wikipedia.org/wiki/Charles_P._Thacker Charles Thacker] has won for the creation of the modern vision of the personal computer (the Xerox Alto) plus Ethernet and the laser printer. | ||
+ | |||
+ | ==== that can't be fake ==== | ||
+ | when i first saw [http://www.vimeo.com/7809605 this] CGI video, i had trouble believing it was all pure CGI. but it is, created with [http://usa.autodesk.com/adsk/servlet/pc/index?siteID=123112&id=13567410 3dsmax], [http://www.chaosgroup.com/en/2/index.html Vray], [http://www.adobe.com/products/aftereffects/ AfterEffects], and [http://www.adobe.com/products/premiere/ Premiere]. [http://vimeo.com/8200251 here is] a related video of the underlying compositing breakdown. | ||
− | ==== | + | ==== Lamarck was actually (sort of) right ==== |
− | [ | + | important trend in inheritance and genetics science... [http://en.wikipedia.org/wiki/Epigenetics#Epigenetic_effects_in_humans transgenerational epigenetics] and genomic imprinting. The upshot is that DNA is not the only factor in genetics and inheritance. ''Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance''. Briefly, without changing the content of the DNA, the on/off expression of genes can be altered by a wide variety of environmental factors. The two major factors that control that gene expression are DNA methylation and histone modifications (think of them as surface control switches on the outside of the DNA, in the critically important mis-named "junk DNA" regions, although that is not literally true). This modification of gene expression in response to environmental factors (such as toxin exposure or starving) has been known for quite some time. BUT it was assumed that these modifications were NOT inherited to children. Wrong. |
− | + | Now, a slew of solid data shows that the genomic imprinting in a parent in response to an environmental factor can be inherited on to the children -- the imprinting survives DNA replication (transcription). | |
− | + | For example, to quote Wikipedia in one of the most well-known studies: | |
− | |||
− | ' | + | ''Marcus Pembrey and colleagues also observed that the paternal (but not maternal) grandsons of Swedish boys who were exposed during preadolescence to famine in the 19th century were less likely to die of cardiovascular disease; if food was plentiful then diabetes mortality in the grandchildren increased, suggesting that this was a transgenerational epigenetic inheritance. The opposite effect was observed for females -- the paternal (but not maternal) granddaughters of women who experienced famine while in the womb (and their eggs were being formed) lived shorter lives on average.'' |
− | + | When does a potential parent create the conditions to pass on environmentally imprinted epigenetics? | |
− | + | In the case of human females, it is when they are themselves in utero and their eggs are forming. If pregnant mom ''Jill'' is starving, this can cause imprinting onto the surface of the DNA of newly-forming eggs in her female in utero baby ''Jane''. When Jane grows up and gets pregnant, her egg's DNA still has the imprinting. When her child Bob is born, his DNA carries this imprinting. | |
− | + | In the case of human males, the environmental factor must happen to the male shortly before puberty, just before the onset of spermatogenesis. | |
− | |||
− | + | Lamarck was wrong in the sense that the causal factor of imprinting (e.g., famine) does not mean successors are skinny (or whatever). A successor may have a higher incidence of bladder cancer (or whatever). | |
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− | + | But, nevertheless, we now know that Lamarck's idea carried a germ of truth, and this is perhaps a paradigm shift in our thinking about personal behavior, the quality of our environment, and our future generations: ''We are guardians of our genetics for successors. By our actions or environment there is a chance our future generations will experience some consequence.'' | |
− | + | ==== plop ==== | |
+ | [[image:oil.jpg|320 px]] | ||
+ | more beautiful images [http://www.sciam.com/includes/gallery_pop.cfm?file=721D7D3A-E7F2-99DF-34810694D5886C2A here]. | ||
==== bird brains ==== | ==== bird brains ==== | ||
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==== don quixote ==== | ==== don quixote ==== | ||
− | i've been reading Cervantes' Don Quixote, downloaded | + | i've been reading Cervantes' Don Quixote, downloaded from the [http://www.gutenberg.org Project Gutenberg] site of many free older books. The translator's notes are a fascinating insight into the historical context of his critical parody. Translated with skill, Cervantes is revealed as an exquisitely gifted writer. He can shape a character rich with implication in few sentences. Don't miss this wonderful classic story. |
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==== wave particles ==== | ==== wave particles ==== | ||
Even after all these years, the strange nature of reality and [http://en.wikipedia.org/wiki/Wave-particle_duality wave-particle duality], | Even after all these years, the strange nature of reality and [http://en.wikipedia.org/wiki/Wave-particle_duality wave-particle duality], | ||
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it suggests links between a women's perception of the environment and | it suggests links between a women's perception of the environment and | ||
sex selection. | sex selection. | ||
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==== green ==== | ==== green ==== | ||
− | Green tea | + | Green tea good. A [http://news.com.au/common/story_page/0,4057,7776384%255E1702,00.html recent] study showed strong results that drinking it reduced the risk of prostate |
cancer in men by 2/3! That is an extraordinarily strong effect. A key | cancer in men by 2/3! That is an extraordinarily strong effect. A key | ||
active chemical is Epigallocatechin Gallate (EGCG) and there is now [http://news.bbc.co.uk/2/hi/health/3257237.stm evidence] EGCG | active chemical is Epigallocatechin Gallate (EGCG) and there is now [http://news.bbc.co.uk/2/hi/health/3257237.stm evidence] EGCG | ||
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shows that the protein creatine (used by body builders) is associated | shows that the protein creatine (used by body builders) is associated | ||
with improved memory and intelligence. | with improved memory and intelligence. | ||
+ | |||
+ | | style="padding-left:1em;" | | ||
+ | ==== mark my eyes ==== | ||
+ | [http://www.technologyreview.com/news/529196/what-else-could-smart-contact-lenses-do/ smart contact lenses] are coming within 20 years that will provide computer displays, night vision, etc. google glass -> google eyeball | ||
+ | |||
+ | ==== a new DROP BOX ==== | ||
+ | amazon is doing the R&D to provide delivery of small packages using ''autonomous drones'', within 30 minutes of order. damn, that's interesting. see [https://www.youtube.com/watch?v=-qOBm3Iwlzo here] | ||
+ | |||
+ | ==== Better Pies Through Science ==== | ||
+ | Amy Rowat, a biophysicist at UCLA, reveals how to apply the insights of science to bake a better apple pie, [http://www.nytimes.com/interactive/2013/07/03/dining/science-builds-a-better-pie.html?ref=dining&_r=1& here] | ||
+ | |||
+ | ==== sweet research ==== | ||
+ | to quote from the [http://med.stanford.edu/ism/2013/june/diabetes.html#sthash.FrF22uZy.dpuf article]: DNA ‘reverse’ vaccine reduces levels of immune cells believed responsible for type-1 diabetes. that could lead a breakthrough in type-1. | ||
+ | |||
+ | ==== "I was swallowed by a Hippo..." ==== | ||
+ | who can resist a [http://www.guardian.co.uk/lifeandstyle/2013/may/04/i-was-swallowed-by-a-hippo true news story] that starts with those words? | ||
+ | |||
+ | ==== retched booze ==== | ||
+ | scientists in chile are developing a vaccine that makes a person feel strong nausea when they drink alcohol; could be a revolution in solving alcoholism. | ||
+ | [http://www.fastcoexist.com/1681344/a-new-vaccine-for-drinking-could-keep-alcoholics-sober see here] | ||
+ | |||
+ | ==== geek sex ==== | ||
+ | in keith richards' [http://www.amazon.com/Life-Keith-Richards/dp/B007F7QG0Y/ref=sr_1_1?ie=UTF8&qid=1359352115&sr=8-1&keywords=keith+richards autobiography Life], he says he doesn't know how to proposition a woman because he's never had to. a geek is a person who finds the statistical part of that as interesting as the sexual. | ||
+ | |||
+ | ==== "FTL" travel within general relativity ==== | ||
+ | just recently became aware of an extraordinary theoretical physics proposal: in 1994 mexican physicist [https://en.wikipedia.org/wiki/Miguel_Alcubierre Miguel Alcubierre] published the milestone idea [http://iopscience.iop.org/0264-9381/11/5/001 The Warp Drive: Hyper-Fast Travel Within General Relativity]. | ||
+ | |||
+ | ''It is shown how, within the framework of general relativity and without the introduction of wormholes, it is possible to modify a spacetime in a way that allows a spaceship to travel with an arbitrarily large speed. By a purely local expansion of spacetime behind the spaceship and an opposite contraction in front of it, motion faster than the speed of light as seen by observers outside the disturbed region is possible. The resulting distortion is reminiscent of the `warp drive' of science fiction.'' | ||
+ | |||
+ | [https://www.youtube.com/watch?v=iJZXDEUOao0 this video] illustrates the idea. | ||
+ | |||
+ | but the idea was not seriously followed up, because original calculations of the amount of energy needed to create a "space bubble" with surrounding expansion and contraction of space-time indicated energies on the order of the mass-energy of jupiter. | ||
+ | |||
+ | yet, harold white recently published the paper [http://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/20110015936_2011016932.pdf Warp Field Mechanics 101] with a simpler summary [http://io9.com/5963263/how-nasa-will-build-its-very-first-warp-drive here]. it indicates that in fact with a modification of the energy ring, the energy needs can be dramatically reduced to the levels within the scope of human engineering. | ||
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+ | dr. white is now starting experiments (with lasers and interferometers) to determine the viability to perturb space-time at certain energy levels. | ||
+ | |||
+ | ==== let it be ==== | ||
+ | got prostate cancer? thinking of surgery? perhaps the longest [http://www.telegraph.co.uk/health/healthnews/9233089/Prostate-cancer-surgery-has-no-significant-survival-benefit-study-suggests.html study] (started in 1993, with 731 men) showed that surgery "has no significant survival benefit" over simply "watchful waiting." | ||
+ | |||
+ | ==== robots invent their own language to interact ==== | ||
+ | [http://spectrum.ieee.org/automaton/robotics/artificial-intelligence/lingodroid-robots-invent-their-own-spoken-language what more needs to be said?] | ||
+ | |||
+ | ==== increase in ions and infrared emissions over earthquake epicenter days before quake ==== | ||
+ | hard facts from researchers about earthquake [http://www.technologyreview.com/blog/arxiv/26773/ precursors]. | ||
+ | |||
+ | the causal-chain hypothesis is that | ||
+ | # stresses in a fault release large amounts of radon, whose radioactivity ionises the air. | ||
+ | # water molecules are attracted to ions in the air, which triggers condensation of water. | ||
+ | # condensation releases heat. | ||
+ | |||
+ | |||
+ | ==== the tomato cure ==== | ||
+ | <html> | ||
+ | <img src="http://www.aplnhouston.org/documents/images/pomodorr_timer.jpg" width="70" height="70" /> | ||
+ | </html> | ||
+ | |||
+ | [http://us.lifehacker.com/5798202/the-cognitive-cost-of-doing-things interesting summary] of cognitive cost of mental activity, and related stresses and sources of enervation. | ||
+ | |||
+ | partial cure? apply the [http://www.pomodorotechnique.com/ Pomodoro Technique] from my friend [http://www.francescocirillo.com/fc.html Francesco Cirilio]. useful for email work, programming, writing, taxes, ... | ||
− | ==== | + | ==== political pre-determinism ==== |
− | [http://www. | + | [http://www.cell.com/current-biology/abstract/S0960-9822(11)00289-2 a report in Current Biology] shows evidence that young adults that self-describe as politically liberal or conservative have different brain structures. |
− | + | the self-described conservatives have a larger amygdala (related to fear responses) and ''"respond to threatening situations with more aggression than do liberals and are more sensitive to threatening facial expressions."'' | |
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− | + | the liberals have larger anterior cingulate cortexes, that ''"monitor(s) uncertainty and conflicts."'' | |
− | + | to quote: ''"Thus, it is conceivable that individuals with a larger ACC have a higher capacity to tolerate uncertainty and conflicts, allowing them to accept more liberal views."'' | |
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− | + | in my product development management consulting work, i observe managers have widely differing ability to accept the inherent high level uncertainty and variability of research and development product creation. perhaps there is a correlation to this research. | |
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− | ==== | + | ==== left gazing face bias -- humans ''and dogs'' ==== |
− | + | did you know that when people look at a face their eyes tend to shift left, viewing the person's right side of face? this left-gaze bias only exists when viewing human faces, not any other object. scientists speculate that the right side of the face (fact: faces are asymmetrical) is better at transparently expressing emotional state. | |
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− | + | now, researchers at [http://www.telegraph.co.uk/science/science-news/3354028/Dogs-can-read-emotion-in-human-faces.html the University of Lincoln] have discovered that ''dogs'' do this too -- and only when looking at humans. there is a growing body of research that dogs have evolved specific behaviors only for successful interaction with humans, essentially unique among the animal world. | |
− | [http://www. | ||
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− | + | the pbs science show nova has an interesting show, [http://www.pbs.org/wgbh/nova/nature/dogs-decoded.html Dogs Decoded], that explores this. one can purchase it at Apple iTunes store. | |
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− | ==== | + | ==== 25 jazz greats ==== |
− | + | an interesting list of [http://matadornetwork.com/nights/25-essential-jazz-albums/ 25 essential jazz albums], with commentary. includes great works such as coltrane's ''a love supreme'', and a personal favorite from 1963, ''getz/gilberto''. | |
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− | ==== | + | ==== Simple Suppers on the Tor network and cross-platform UIs ==== |
− | + | if you like cooking, and want good *fast* recipes, the UK's "channel 4" maintains a [http://www.channel4.com/4food great collection] (and associated cooking TV or online videos shows) of quick and simple recipes from Jamie Oliver, Gordon Ramsay and Hugh Fearnley Whittingstall. also, check out nigel slater's [http://www.bbc.co.uk/programmes/b00vt10m Simple Suppers] at BBC. | |
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− | + | if not in the UK and the video content is blocked online, look at [https://www.torproject.org/projects/vidalia.html.en vidalia] and [https://www.torproject.org/ the tor network] to get around the blocks. btw, the UI of vidalia is done with the open-source cross-platform [http://qt.nokia.com/ Qt framework] originally created by two creative norwegian developers, Haavard Nord and Eirik Chambe-Eng (Trolltech); Qt is also used for Skype, Google Earth, and many other applications. | |
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− | ==== | + | ==== sweet for heat ==== |
− | + | not merely a folk remedy belief, there is solid evidence that treating non-major burns with honey is indeed effective. a [http://www.nytimes.com/2008/02/19/health/19real.html meta-study] looked at over 12 previous studies, and concluded that burns healed faster (on average) when treated with honey and gauze, than those treated with antibiotic creams and other dressings | |
− | ==== | + | ==== the social implications of age reversal ==== |
− | + | harvard medical school [http://www.guardian.co.uk/science/2010/nov/28/scientists-reverse-ageing-mice-humans announced] a study not just slowing ageing in mice, but... ''"What we saw in these animals was not a slowing down or stabilisation of the ageing process. We saw a dramatic reversal – and that was unexpected,"'' said Ronald DePinho, who led the study. the work involved an old (no pun intended), well-known mechanism in ageing: telomere shortening over time. it brings a difficult question one step closer: what if old people didn't die? | |
− | + | ||
− | + | ==== mimic octopus ==== | |
− | ==== | + | well beyond interesting, this is the most fascinating animal in the world; you will be delighted to [http://youtu.be/ygh1-ul6E94 watch]. |
− | + | ||
− | + | ==== glycemic load of foods ==== | |
− | + | recently heard that large rolled oats are ''much'' healthier in terms of glycemic load than small, cut oats, for oatmeal (which i like). that got me curious as to the hard data on glycemic load of different foods. here's some credible data, from university of sydney research: http://www.mendosa.com/gilists.htm | |
− | + | ||
− | + | ==== the decay of decay ==== | |
− | + | ||
− | + | [http://www.telegraph.co.uk/health/healthnews/7914009/Gel-for-decayed-teeth-could-spell-end-to-fillings.html research] on a gel, perhaps available within 5 years, that stimulates growth of tooth cells, to replace cavities. | |
− | + | ||
− | + | ==== influenza ==== | |
− | + | ||
− | ==== | + | influenza virus is notoriously mutable on key surface elements, making a universal vaccine tough. but researchers, reporting in [http://www.telegraph.co.uk/science/7893553/Vaccine-that-will-protect-against-every-type-of-flu.html ''Science''] , may have solution. Rather than targeting the lollipop head of the surface protein called haemagglutinin (HA), the new vaccine, to quote, ''generates “universal” antibodies that aim for the “stick” of the HA lollipop, which varies little from strain to strain''. |
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− | ==== | + | ==== engines of democracy ==== |
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− | + | scrum and other agile methods include the principle of self-organizing teams (the 11th agile principle). here is another related story from [http://www.fastcompany.com/magazine/28/ge.html Fast Company] | |
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− | ==== | + | ==== vaccine for breast cancer? ==== |
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− | + | could be [http://www.more.com/8717/22615-a-vaccine-against-breast-cancer interesting] | |
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− | [http://www. | ||
− | + | ==== synthetic life - venter and team ==== | |
− | + | most likely all readers heard this, but it is still worth noting: a milestone in synthetic life. Craig Venter and team have [http://news.bbc.co.uk/2/hi/science_and_environment/10132762.stm created] the DNA for a bacterium completely bottom-up from chemicals, injected the synthetic DNA into a cell, which then started to replicate (over a billion times) using, as usual, the DNA for its replication instructions. | |
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− | + | the long-term implications are extraordinary, as scientists learn to master creating more complex DNA. Exxon is funding the research ($600 million usd) to see if they can create a bug that will create oil. | |
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− | ==== | + | ==== alcohol/etc addiction reduction with Baclofen ==== |
− | |||
− | + | there is some evidence that the muscle relaxant Baclofen (created in the 1920s) can significantly reduce cravings for alcohol -- and perhaps other addictive drugs. Read the fascinating story of [http://www.guardian.co.uk/society/2010/may/09/alcoholism-health-doctor-addiction-drug Dr. Ameisen] that has a happy ending. | |
− | |||
− | + | ==== it sucks ==== | |
− | + | doctors have discovered that negative pressure (suction) on a wound speeds healing. the cause is not known, but may be due to removal of fluid buildup. there is an existing device for this therapy, costing over $100, but an mit student has created a [http://inhabitat.com/2010/04/15/3-healing-device-speeds-up-wound-treatment/ $3 device] that achieves the same goal. | |
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− | + | ==== coma -> german ==== | |
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− | + | another intriguing example of the mysteries of the human brain: to quote [http://www.telegraph.co.uk/news/worldnews/europe/croatia/7583971/Croatian-teenager-wakes-from-coma-speaking-fluent-German.html the story]... ''A 13-year-old Croatian girl who fell into a coma woke up speaking fluent German. The girl, from the southern town of Knin, had only just started studying German at school and had been reading German books and watching German TV to become better, but was by no means fluent, according to her parents. Since waking up from her 24 hour coma however, she has been unable to speak Croatian, but is able to communicate perfectly in German.'' | |
− | + | ==== random matrix theory ==== | |
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+ | [http://en.wikipedia.org/wiki/Random_matrix_theory random matrix theory], first proposed by the physicist [http://en.wikipedia.org/wiki/Eugene_Wigner Eugene Wigner] to help determine the probability of a particle moving between discrete energy level states, has been shown to apply, as a model, to a broad range of systems, including the mathematics of certain games of solitaire, the clumping of buses in traffic, and the path traced by molecules moving in a gas. and perhaps most importantly as we enter the age of easy access to massive sets of data (think, Google's collection of statistics), random matrix theory can help distinguish meaningful causal relationships from those that are not, in the case when traditional statistical methods showed "false positives" regarding meaningful correlation. to quote a [http://www.newscientist.com/article/mg20627550.200-enter-the-matrix-the-deep-law-that-shapes-our-reality.html?DCMP=OTC-rss recent story]: | ||
− | + | '''Bouchaud's team has now shown how [the idea that larger data sets leads to better predictions] throws doubt on the trustworthiness of many economic predictions, especially those claiming to look many months ahead. Such predictions are, of course, the bread and butter of economic institutions. But can we believe them?'' | |
− | + | ''To find out, Bouchaud and his colleagues looked at how well US inflation rates could be explained by a wide range of economic indicators, such as industrial production, retail sales, consumer and producer confidence, interest rates and oil prices.'' | |
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− | + | ''Using figures from 1983 to 2005, they first calculated all the possible correlations among the data. They found [using traditional statistical validity tests] what seem to be significant results - apparent patterns showing how changes in economic indicators at one moment lead to changes in inflation the next. To the unwary observer, this makes it look as if inflation can be predicted with confidence.'' | |
− | the | ||
− | + | ''But when Bouchaud's team applied Marcenko's and Pastur's mathematics [influenced by random matrix theory], they got a surprise. They found that only a few of these apparent correlations can be considered real, in the sense that they really stood out from what would be expected by chance alone. Their results show that inflation is predictable only one month in advance. Look ahead two months and the mathematics shows no predictability at all. '''Adding more data just doesn't lead to more predictability as some economists would hope''', says Bouchaud.'' | |
− | + | ==== a breathless discovery ==== | |
− | + | in a discovery further opening the possibilties of extra-terrestrial life, researchers have [http://www.wired.com/wiredscience/2010/04/anoxic-animals/ found], in the deep Mediterranean seafloor, the first multicellular animals capable of surviving in an entirely oxygen-free environment. the Loricifera species have hydrogenosomes, which require no oxygen to produce chemical energy. they have no mitochondria, the mechanism of other animal cell, that converts oxygen (and other stuff) into energy. | |
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− | ==== | + | ==== quantum teleportation of energy ==== |
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− | + | teleportation of information is a fascinating subject, based on [http://en.wikipedia.org/wiki/Quantum_entanglement quantum entanglement]. Now, a scientist has [http://www.physorg.com/news184597481.html proposed] a model of teleportation of energy; the implications are interesting. to quote: | |
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− | + | ''There is a growing sense that the properties of the universe are best described not by the laws that govern matter but by the laws that govern information. This appears to be true for the quantum world, is certainly true for special relativity, and is currently being explored for general relativity.'' | |
− | + | ==== light boom ==== | |
− | + | 2012 could be a milestone year in fusion: the year that the [http://en.wikipedia.org/wiki/National_Ignition_Facility National Ignition Facility] hopes to achieve ''controlled fusion with a net energy gain'' by firing many lasers at a small target of deuterium and tritium. | |
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− | ==== | + | ==== internal mental activity by a BBD? ==== |
− | + | is [http://vesicle.nsi.edu/users/izhikevich/publications/large-scale_model_of_human_brain.htm this] the first example of independent "mental" activity by an artificial brain-based device? don't be put off by the academic dry title; read carefully the second-to-last sentence in the abstract to grasp the implications of what is really being reported. the author Gerald M. Edelman is the winner of a 1972 Nobel prize. afaik, it is also the largest neural simulation created. | |
+ | |||
+ | ==== Thru You ==== | ||
+ | read [http://www.huffingtonpost.com/timothy-karr/the-future-begins-thru-yo_b_174483.html this], and then see the linked "thru you" [http://www.thru-you.com/# music videos] (my favourites are tracks 1, 5, and 7) . the musician has composed new music by only mixing stuff from youtube. that might sound "simple," but when i saw it, it seemed to me he has raised this mixing to a new level of creative art. | ||
− | ==== | + | ==== computational intelligence deduces a law of physics ==== |
− | + | my grad degree was in AI-related subjects (having little of my own), so this research and video struck me as quite interesting. the algorithm identified several laws of physics (without prior information about the domains) by analyzing data of objects in motion. See [http://www.guardian.co.uk/science/2009/apr/02/eureka-laws-nature-artificial-intelligence-ai here]. | |
− | ==== | + | ==== transparency ==== |
− | + | [[image:ButterflyGlasswing.jpg|320 px]] | |
+ | i just discovered the existence of Glass Wing Butterflies. lovely. | ||
− | ==== | + | ==== fun ==== |
− | + | [http://www.youtube.com/watch?v=PmZyB_ghpa0 this] is striking. | |
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− | ==== | + | ==== why don't they just fly first class? ==== |
− | + | the 2007 [http://www.improbable.com/ig/ ignoble awards] are out, including: | |
− | + | * The US Air Force Wright Laboratory for instigating research and development on a chemical weapon that would provoke widespread homosexual behaviour among enemy troops. | |
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− | + | * A National University of Quilmes, Argentina, team for discovering that impotency drugs can help hamsters to recover from jet lag. | |
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− | ==== | + | ==== explain to me how you forget your leg? ==== |
− | + | any [http://news.bbc.co.uk/2/hi/americas/7024124.stm story] that begins "A US man who stored his amputated leg in a barbecue smoker..." just sort of begs to be read. | |
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Latest revision as of 14:49, 31 January 2019
My blog on idiosyncratically interesting things...
psychological and neurological influence on R&D management style?over the last 10+ years there's been a growing body of evidence related to political, economic, and religious conservatism and brain structures or cognitive behavior related to sensitivity to perceived negative, uncertain, or ambiguous information. for example, there's the 2014 study Nonpolitical Images Evoke Neural Predictors of Political Ideology published in Cell-Current Biology. To quote the researchers, "This is the first fMRI study revealing multivariate patterns of brain activity that differ between liberals and conservatives during emotional processing of sensory stimuli. A single disgusting image was sufficient to predict each subject's political orientation" with 94% accuracy, Montague told Cell Press. I haven't seen such clean predictive results in any other functional imaging experiments in our lab or others." in other words, apparent 'conscious' and 'deliberative' decisions about political ideology are connected strongly to very primitive parts of the brain involved in aversion or fear responses. another study: a 2014 study shows that self-reported conservatives respond with fear much more rapidly to what they perceive as aversive or threatening stimuli. linking to neurology, a report in Current Biology shows evidence that young adults that self-describe as politically liberal or conservative have different brain structures. the self-described conservatives have a larger amygdala (related to fear responses) and "respond to threatening situations with more aggression than do liberals and are more sensitive to threatening facial expressions." the liberals have larger anterior cingulate cortexes, that "monitor(s) uncertainty and conflicts." to quote: "Thus, it is conceivable that individuals with a larger ACC have a higher capacity to tolerate uncertainty and conflicts, allowing them to accept more liberal views." linking back to psychology research is a published synthesis of existing psychological studies on ideology, shows a pattern of evidence that conservatives are characterized by traits such as a need for certainty and an intolerance of ambiguity. and there's related research on the lack of tolerance of ambiguity and the need for certainty being stronger amongst self-reported conservatives. as mentioned in another blog post, in my product development management consulting work, i observe managers have widely differing ability to accept the inherent high level uncertainty and variability of research and development product creation. some really want R&D to be "predictable manufacturing" and have psychological discomfort with a domain of uncertainty that requires feedback loops, learning, and revision of prior information (estimates, requirements, ...). perhaps there is a correlation to this research. a fast way to stem-cell-based regenerationResearch published in Cell Stem Cell that a minimum 48-hour fast helps "regenerate" the immune system, and a minimum 72-hour fast helped recovery during chemotherapy. Rinse & repeat every 6 months. how to survive a plane crash & cognitive biasmost people will be drawn to read this article on surviving a plane crash as an example of cognitive bias, even though they are more likely to die in a car crash. this cognitive bias is an example of a larger set:
and wikipedia has a wonderful list of over *SIXTY* kinds of cognitive bias. related are the insights of charlie munger, the partner of warren buffet ("the greatest investor") in his 1995 harvard talk Twenty Four Standard Causes of Human Misjudgement could be big (meaning, little)University of Illinois researchers have created a breakthrough battery technology orders of magnitude smaller and more powerful. here's the story. 30 gram micro-drone with camera; bionic dragonflynot hard to see the trajectory of this technology. even the first generation micro-drone with 30 minutes of flying time with real-time transmission of video is a mere 30 grams. imagine in 10 years. these have now been issued to british soldiers in combat zones. video here and here is a bionic dragonfly, which will be commercialized soon. amazing hard data on dominant cause of unhappiness: wandering mindfor his phd research at harvard in 2012, matt killingsworth used mobile app and big data tools to identify a dominant cause (not just correlate) of unhappiness: a wandering mind not focussed in the sensations of the present moment. watch the TED talk here. he did not discuss therapies or mental tools, but there are several. for example, charlotte selver was a music educator who founded and promoted sensory awareness training, that led to variants such as body awareness therapy and somatic therapy, and mindfulness-based stress reduction (coming from the university of massachusetts medical school). going farther back, "mindfulness of physical sensations" (such as breathing, touch pressure, etc.) is a buddhist practice in the theravada school (the oldest branch of the doctrine) and practiced in 'mindfulness' retreats. scientific evidence of absence of free willif you choose to click this link and read the evidence, who made that choice? cheating with 'undetectable' chess computer aidin bulgaria in dec 2012 a chess tournament was held in which a player displayed a leap of improved playing that was so suspicious that organizers suspect aid from a computer. but it was not possible to detect anything on the player in question. people speculate about an under-the-skin implant that transmits information, but there is no proof. what is interesting about this story is that it is the first harbinger of things to come, more broadly in the area of bionics and neuro-prosthetics. one analyst presents an interesting study on how to evaluate if the cheater was using a computer, with statistics. read here. causation vs. correlationconvergent cross mapping. a research result that might not sound a milestone, but probably is: finally, a solid mathematical model to answer the question, "Is there a causal relationship between 2 factors?". And that answer can now be provided (for biological and eco systems), even without knowing the details of the underlying mechanisms. summarized in the paper Detecting Causality in Complex Ecosystems. is it real -- or Memorex?perhaps if you read the original Nature Neuroscience title, Mnemonic representations of transient stimuli and temporal sequences in the rodent hippocampus in vitro, the fact and implications may not be clear. how about this summary? Scientists Invent Method to Create Memories in Brains. wow. MIT people see more clearlycould be big: to quote, "MIT researchers find a way to make glass that’s anti-fogging, self-cleaning and free of glare." the advanced british spy servicehard to resist a headline that reads "Sadomasochism interest no barrier to dead spy joining MI6". how do they do the interviews? bionic eye patient tests planned for 2013link here. what more to say? we live in amazing times. discovered? the mechanism of memory encodingthis research could be a profound milestone in science; it hints at the real core, subtle mechanism of memory encoding. it involves interaction of calcium-calmodulin dependent kinase complex II and tubulin protein compounds, which occupy the interiors of brain neurons. cancer "cure" ignored due to no profit?interesting story out of the University of Alberta, regarding dichloroacetic acid. Here'a related news story on the profit motive and lack of follow-up research. influenza A antibodyone vaccine for all forms of influenza A is a long-sought goal. researchers now report the discovery of FI6 antibody that binds to and neutralizes all subtypes. to find a potential antibody, they used a "wide search" strategy single-cell culture method to screen 100,000 plasma cells from eight human donors. Four of those 100,000 cells "from one donor yielded an antibody that reacted with H1, H5, and H7 viruses." who can resist reading a news items titled...Harry Potter dwarf spared jail over juggler's hat sex act brain on a plateresearchers at the university of pittsburgh have grown an active "living" partial rat brain in a dish. bigprediction: within 20 years, something like this is going to be huge. this is an entire mobile phone based on this important trend. this will revolutionize the form factor of devices. probably in tube or scroll-style -- check out seconds 42-49 in the first video. longer term? probably the ability to replace the biological lens of the eyeball with artificial lens that display (via wireless signals) images. nobiletinnobiletin, found in the skin of tangerines, is a citrus flavonoid recently shown in mice studies to have strongly attenuated atherosclerosis and VLDL overproduction, and reduced obesity. 800 lumens, 20 years, 8 wattsthere is some very tentative research that CFL lights may have carcinogenic issues, but fortunately, LED home lighting is now emerging. no, no, nothe youtube commenter probably said it best, "if he fell he would probably land on his gigantic balls and survive." this is just a little out of my comfort zone. the magicianthe wonderful, colorful physicist richard feynman gave a series of lectures on physics, that have long been famous for their approach. they are now online, and well worth watching. at los alamos, during the a-bomb project, the science leader oppenheimer said of feynman (and consider the competition there!), "He is by all odds the most brilliant young physicist here, and everyone knows this". online documentarieswhile surfing for the Watson AI video, stumbled across a nice streaming documentary site, that organizes videos mostly from youtube: DocumentaryStorm an AI milestonethe "AI" system Watson created by researchers at IBM and several universities, that won the Jeopardy! TV game show, is the first example seen (observing since the 1970s) of a computer system that made me go, "wow, finally getting somewhere interesting with AI research." will be fascinating to see how the "deep QA" ideas applied in Watson are put to practical use; for example, IBM is now implementing "medical Watson" for commercialization. never too oldgood for him! and good for her coach potato marathon mouseslim, healthy, super fit endurance athlete body -- not by exercising, but by AICAR? salk institute researchers discovered that a key dynamic of slow-twitch muscle endurance exercise (e.g., jogging) is that it triggers the development of more mitochondria that burn fat. and AICAR stimulates this same biochemical process, stimulating the creation of more slow-twitch muscles and fat-burning mitochondria. they did an experiment with mice that were sedentary for months, but fed AICAR daily. the first noteworthy thing was that the coach-potato mice remained slim and healthy looking. and then, without any prior exercise or training, the coach potato mice were put in a high-endurance marathon tread mill run -- and were immediately a champion "marathon mice" that could exercise for a long. as the researchers point out, this drug could be useful for old people or others who are temporarily bed ridden and quickly losing muscle tone. where did i leave my walking shoes?a recent study published in PNAS showed that 40 minutes 3 times per week (for 1 year) of brisk walking (an aerobic activity) for a group of (prior-sedentary) seniors increased hippocampal and medial temporal lobe volumes by 2%, and was concomitantly associated with improved cognitive/memory function. OTOH, a matched group that only did stretching exercises degraded. e-eyesinteresting for bifocal or progressive glass lens wearers: the introduction of dynamic electronic focusing lens, emPower. the technology is described as "the single most significant advancement in prescription eyewear in the last 50 years" -- that might be true. fists of fury?a study published in journal of consumer research showed that clenching muscles (such as a fist) was associated with increased self-control, such as resisting your third helping of chocolate mousse. To quote: Participants who were instructed to tighten their muscles, regardless of which muscles they tightened—hand, finger, calf, or biceps—while trying to exert self-control demonstrated greater ability to withstand the pain, consume the unpleasant medicine, attend to the immediately disturbing but essential information, or overcome tempting foods. Thacker -- Turing awardanother PARC alumni (in addition to Alan Kay and Butler Lampson) has won the Turing award. Charles Thacker has won for the creation of the modern vision of the personal computer (the Xerox Alto) plus Ethernet and the laser printer. that can't be fakewhen i first saw this CGI video, i had trouble believing it was all pure CGI. but it is, created with 3dsmax, Vray, AfterEffects, and Premiere. here is a related video of the underlying compositing breakdown. Lamarck was actually (sort of) rightimportant trend in inheritance and genetics science... transgenerational epigenetics and genomic imprinting. The upshot is that DNA is not the only factor in genetics and inheritance. Genomic imprinting is an inheritance process independent of the classical Mendelian inheritance. Briefly, without changing the content of the DNA, the on/off expression of genes can be altered by a wide variety of environmental factors. The two major factors that control that gene expression are DNA methylation and histone modifications (think of them as surface control switches on the outside of the DNA, in the critically important mis-named "junk DNA" regions, although that is not literally true). This modification of gene expression in response to environmental factors (such as toxin exposure or starving) has been known for quite some time. BUT it was assumed that these modifications were NOT inherited to children. Wrong. Now, a slew of solid data shows that the genomic imprinting in a parent in response to an environmental factor can be inherited on to the children -- the imprinting survives DNA replication (transcription). For example, to quote Wikipedia in one of the most well-known studies: Marcus Pembrey and colleagues also observed that the paternal (but not maternal) grandsons of Swedish boys who were exposed during preadolescence to famine in the 19th century were less likely to die of cardiovascular disease; if food was plentiful then diabetes mortality in the grandchildren increased, suggesting that this was a transgenerational epigenetic inheritance. The opposite effect was observed for females -- the paternal (but not maternal) granddaughters of women who experienced famine while in the womb (and their eggs were being formed) lived shorter lives on average. When does a potential parent create the conditions to pass on environmentally imprinted epigenetics? In the case of human females, it is when they are themselves in utero and their eggs are forming. If pregnant mom Jill is starving, this can cause imprinting onto the surface of the DNA of newly-forming eggs in her female in utero baby Jane. When Jane grows up and gets pregnant, her egg's DNA still has the imprinting. When her child Bob is born, his DNA carries this imprinting. In the case of human males, the environmental factor must happen to the male shortly before puberty, just before the onset of spermatogenesis. Lamarck was wrong in the sense that the causal factor of imprinting (e.g., famine) does not mean successors are skinny (or whatever). A successor may have a higher incidence of bladder cancer (or whatever). But, nevertheless, we now know that Lamarck's idea carried a germ of truth, and this is perhaps a paradigm shift in our thinking about personal behavior, the quality of our environment, and our future generations: We are guardians of our genetics for successors. By our actions or environment there is a chance our future generations will experience some consequence. plopmore beautiful images here. bird brainsRecent research suggests that birds 'see' magnetic fields. Studies investigating what parts of a migratory bird´s brain are active when the birds use their magnetic compass showed that the cryptochrome-containing neurons in the eye and a forebrain region are highly active during processing of magnetic compass information in migratory birds. causal loops and systems dynamicsMany of the groups I serve with don't have a concrete tool to explore and discuss what's going on in their organizations, in terms of the dynamics of the system. Most of us have been well-trained in details analysis and management, but not dynamics analysis. Getting together at a whiteboard and sketching causal loop diagrams can help. see. don quixotei've been reading Cervantes' Don Quixote, downloaded from the Project Gutenberg site of many free older books. The translator's notes are a fascinating insight into the historical context of his critical parody. Translated with skill, Cervantes is revealed as an exquisitely gifted writer. He can shape a character rich with implication in few sentences. Don't miss this wonderful classic story. wave particlesEven after all these years, the strange nature of reality and wave-particle duality, as illustrated in the 2-slit experiment, remains amazing. Its not really “particles” down there... both "waves" and "particles" are just metaphors for a quantum micro-level reality that doesn't conform to our intuitions of how the macro-level world works. baby boysI found this fascinating: Did you know that after World War I, after so many million males had been killed, that for some time women in the related countries gave birth to significantly more males than females? As though nature had a way to re-balance. How could that work? Recent research (I can't find the link now...) shows that women are less likely to give birth to males when there is stress, probably because males were more of an evolutionary risk (more likely to get killed). The relationship to the WWI story doesn't make sense yet, but broadly it suggests links between a women's perception of the environment and sex selection. greenGreen tea good. A recent study showed strong results that drinking it reduced the risk of prostate cancer in men by 2/3! That is an extraordinarily strong effect. A key active chemical is Epigallocatechin Gallate (EGCG) and there is now evidence EGCG stops HIV binding to cells. A variety of studies show it is correlated with lower rates of various cancers, reduces the risk of rheumatoid arthritis and lowers cholesterol levels. alpha-lipoic acidIn addition to research showing that taking acetyl-L-carnitine and alpha-lipoic acid is associated with improved cognitive function, new research shows that the protein creatine (used by body builders) is associated with improved memory and intelligence. |
mark my eyessmart contact lenses are coming within 20 years that will provide computer displays, night vision, etc. google glass -> google eyeball a new DROP BOXamazon is doing the R&D to provide delivery of small packages using autonomous drones, within 30 minutes of order. damn, that's interesting. see here Better Pies Through ScienceAmy Rowat, a biophysicist at UCLA, reveals how to apply the insights of science to bake a better apple pie, here sweet researchto quote from the article: DNA ‘reverse’ vaccine reduces levels of immune cells believed responsible for type-1 diabetes. that could lead a breakthrough in type-1. "I was swallowed by a Hippo..."who can resist a true news story that starts with those words? retched boozescientists in chile are developing a vaccine that makes a person feel strong nausea when they drink alcohol; could be a revolution in solving alcoholism. see here geek sexin keith richards' autobiography Life, he says he doesn't know how to proposition a woman because he's never had to. a geek is a person who finds the statistical part of that as interesting as the sexual. "FTL" travel within general relativityjust recently became aware of an extraordinary theoretical physics proposal: in 1994 mexican physicist Miguel Alcubierre published the milestone idea The Warp Drive: Hyper-Fast Travel Within General Relativity. It is shown how, within the framework of general relativity and without the introduction of wormholes, it is possible to modify a spacetime in a way that allows a spaceship to travel with an arbitrarily large speed. By a purely local expansion of spacetime behind the spaceship and an opposite contraction in front of it, motion faster than the speed of light as seen by observers outside the disturbed region is possible. The resulting distortion is reminiscent of the `warp drive' of science fiction. this video illustrates the idea. but the idea was not seriously followed up, because original calculations of the amount of energy needed to create a "space bubble" with surrounding expansion and contraction of space-time indicated energies on the order of the mass-energy of jupiter. yet, harold white recently published the paper Warp Field Mechanics 101 with a simpler summary here. it indicates that in fact with a modification of the energy ring, the energy needs can be dramatically reduced to the levels within the scope of human engineering. dr. white is now starting experiments (with lasers and interferometers) to determine the viability to perturb space-time at certain energy levels. let it begot prostate cancer? thinking of surgery? perhaps the longest study (started in 1993, with 731 men) showed that surgery "has no significant survival benefit" over simply "watchful waiting." robots invent their own language to interactincrease in ions and infrared emissions over earthquake epicenter days before quakehard facts from researchers about earthquake precursors. the causal-chain hypothesis is that
the tomato cure<html> <img src="http://www.aplnhouston.org/documents/images/pomodorr_timer.jpg" width="70" height="70" /> </html> interesting summary of cognitive cost of mental activity, and related stresses and sources of enervation. partial cure? apply the Pomodoro Technique from my friend Francesco Cirilio. useful for email work, programming, writing, taxes, ... political pre-determinisma report in Current Biology shows evidence that young adults that self-describe as politically liberal or conservative have different brain structures. the self-described conservatives have a larger amygdala (related to fear responses) and "respond to threatening situations with more aggression than do liberals and are more sensitive to threatening facial expressions." the liberals have larger anterior cingulate cortexes, that "monitor(s) uncertainty and conflicts." to quote: "Thus, it is conceivable that individuals with a larger ACC have a higher capacity to tolerate uncertainty and conflicts, allowing them to accept more liberal views." in my product development management consulting work, i observe managers have widely differing ability to accept the inherent high level uncertainty and variability of research and development product creation. perhaps there is a correlation to this research. left gazing face bias -- humans and dogsdid you know that when people look at a face their eyes tend to shift left, viewing the person's right side of face? this left-gaze bias only exists when viewing human faces, not any other object. scientists speculate that the right side of the face (fact: faces are asymmetrical) is better at transparently expressing emotional state. now, researchers at the University of Lincoln have discovered that dogs do this too -- and only when looking at humans. there is a growing body of research that dogs have evolved specific behaviors only for successful interaction with humans, essentially unique among the animal world. the pbs science show nova has an interesting show, Dogs Decoded, that explores this. one can purchase it at Apple iTunes store. 25 jazz greatsan interesting list of 25 essential jazz albums, with commentary. includes great works such as coltrane's a love supreme, and a personal favorite from 1963, getz/gilberto. Simple Suppers on the Tor network and cross-platform UIsif you like cooking, and want good *fast* recipes, the UK's "channel 4" maintains a great collection (and associated cooking TV or online videos shows) of quick and simple recipes from Jamie Oliver, Gordon Ramsay and Hugh Fearnley Whittingstall. also, check out nigel slater's Simple Suppers at BBC. if not in the UK and the video content is blocked online, look at vidalia and the tor network to get around the blocks. btw, the UI of vidalia is done with the open-source cross-platform Qt framework originally created by two creative norwegian developers, Haavard Nord and Eirik Chambe-Eng (Trolltech); Qt is also used for Skype, Google Earth, and many other applications. sweet for heatnot merely a folk remedy belief, there is solid evidence that treating non-major burns with honey is indeed effective. a meta-study looked at over 12 previous studies, and concluded that burns healed faster (on average) when treated with honey and gauze, than those treated with antibiotic creams and other dressings the social implications of age reversalharvard medical school announced a study not just slowing ageing in mice, but... "What we saw in these animals was not a slowing down or stabilisation of the ageing process. We saw a dramatic reversal – and that was unexpected," said Ronald DePinho, who led the study. the work involved an old (no pun intended), well-known mechanism in ageing: telomere shortening over time. it brings a difficult question one step closer: what if old people didn't die? mimic octopuswell beyond interesting, this is the most fascinating animal in the world; you will be delighted to watch. glycemic load of foodsrecently heard that large rolled oats are much healthier in terms of glycemic load than small, cut oats, for oatmeal (which i like). that got me curious as to the hard data on glycemic load of different foods. here's some credible data, from university of sydney research: http://www.mendosa.com/gilists.htm the decay of decayresearch on a gel, perhaps available within 5 years, that stimulates growth of tooth cells, to replace cavities. influenzainfluenza virus is notoriously mutable on key surface elements, making a universal vaccine tough. but researchers, reporting in Science , may have solution. Rather than targeting the lollipop head of the surface protein called haemagglutinin (HA), the new vaccine, to quote, generates “universal” antibodies that aim for the “stick” of the HA lollipop, which varies little from strain to strain. engines of democracyscrum and other agile methods include the principle of self-organizing teams (the 11th agile principle). here is another related story from Fast Company vaccine for breast cancer?could be interesting synthetic life - venter and teammost likely all readers heard this, but it is still worth noting: a milestone in synthetic life. Craig Venter and team have created the DNA for a bacterium completely bottom-up from chemicals, injected the synthetic DNA into a cell, which then started to replicate (over a billion times) using, as usual, the DNA for its replication instructions. the long-term implications are extraordinary, as scientists learn to master creating more complex DNA. Exxon is funding the research ($600 million usd) to see if they can create a bug that will create oil. alcohol/etc addiction reduction with Baclofenthere is some evidence that the muscle relaxant Baclofen (created in the 1920s) can significantly reduce cravings for alcohol -- and perhaps other addictive drugs. Read the fascinating story of Dr. Ameisen that has a happy ending. it sucksdoctors have discovered that negative pressure (suction) on a wound speeds healing. the cause is not known, but may be due to removal of fluid buildup. there is an existing device for this therapy, costing over $100, but an mit student has created a $3 device that achieves the same goal. coma -> germananother intriguing example of the mysteries of the human brain: to quote the story... A 13-year-old Croatian girl who fell into a coma woke up speaking fluent German. The girl, from the southern town of Knin, had only just started studying German at school and had been reading German books and watching German TV to become better, but was by no means fluent, according to her parents. Since waking up from her 24 hour coma however, she has been unable to speak Croatian, but is able to communicate perfectly in German. random matrix theoryrandom matrix theory, first proposed by the physicist Eugene Wigner to help determine the probability of a particle moving between discrete energy level states, has been shown to apply, as a model, to a broad range of systems, including the mathematics of certain games of solitaire, the clumping of buses in traffic, and the path traced by molecules moving in a gas. and perhaps most importantly as we enter the age of easy access to massive sets of data (think, Google's collection of statistics), random matrix theory can help distinguish meaningful causal relationships from those that are not, in the case when traditional statistical methods showed "false positives" regarding meaningful correlation. to quote a recent story: 'Bouchaud's team has now shown how [the idea that larger data sets leads to better predictions] throws doubt on the trustworthiness of many economic predictions, especially those claiming to look many months ahead. Such predictions are, of course, the bread and butter of economic institutions. But can we believe them? To find out, Bouchaud and his colleagues looked at how well US inflation rates could be explained by a wide range of economic indicators, such as industrial production, retail sales, consumer and producer confidence, interest rates and oil prices. Using figures from 1983 to 2005, they first calculated all the possible correlations among the data. They found [using traditional statistical validity tests] what seem to be significant results - apparent patterns showing how changes in economic indicators at one moment lead to changes in inflation the next. To the unwary observer, this makes it look as if inflation can be predicted with confidence. But when Bouchaud's team applied Marcenko's and Pastur's mathematics [influenced by random matrix theory], they got a surprise. They found that only a few of these apparent correlations can be considered real, in the sense that they really stood out from what would be expected by chance alone. Their results show that inflation is predictable only one month in advance. Look ahead two months and the mathematics shows no predictability at all. Adding more data just doesn't lead to more predictability as some economists would hope, says Bouchaud. a breathless discoveryin a discovery further opening the possibilties of extra-terrestrial life, researchers have found, in the deep Mediterranean seafloor, the first multicellular animals capable of surviving in an entirely oxygen-free environment. the Loricifera species have hydrogenosomes, which require no oxygen to produce chemical energy. they have no mitochondria, the mechanism of other animal cell, that converts oxygen (and other stuff) into energy. quantum teleportation of energyteleportation of information is a fascinating subject, based on quantum entanglement. Now, a scientist has proposed a model of teleportation of energy; the implications are interesting. to quote: There is a growing sense that the properties of the universe are best described not by the laws that govern matter but by the laws that govern information. This appears to be true for the quantum world, is certainly true for special relativity, and is currently being explored for general relativity. light boom2012 could be a milestone year in fusion: the year that the National Ignition Facility hopes to achieve controlled fusion with a net energy gain by firing many lasers at a small target of deuterium and tritium. internal mental activity by a BBD?is this the first example of independent "mental" activity by an artificial brain-based device? don't be put off by the academic dry title; read carefully the second-to-last sentence in the abstract to grasp the implications of what is really being reported. the author Gerald M. Edelman is the winner of a 1972 Nobel prize. afaik, it is also the largest neural simulation created. Thru Youread this, and then see the linked "thru you" music videos (my favourites are tracks 1, 5, and 7) . the musician has composed new music by only mixing stuff from youtube. that might sound "simple," but when i saw it, it seemed to me he has raised this mixing to a new level of creative art. computational intelligence deduces a law of physicsmy grad degree was in AI-related subjects (having little of my own), so this research and video struck me as quite interesting. the algorithm identified several laws of physics (without prior information about the domains) by analyzing data of objects in motion. See here. transparencyi just discovered the existence of Glass Wing Butterflies. lovely. funthis is striking. why don't they just fly first class?the 2007 ignoble awards are out, including:
explain to me how you forget your leg?any story that begins "A US man who stored his amputated leg in a barbecue smoker..." just sort of begs to be read.
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